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KMID : 0361520000110020100
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Korean Journal of Psychopharmacology
2000 Volume.11 No. 2 p.100 ~ p.110
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A Recent Review of Tardive Dyskinesia
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1/2이상경/12Sang Kyeong Lee
1/2김영훈/12Young Hoon Kim
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Abstract
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-Abstract-
Long-term treatment with antipsychotic can sometimes lead to a irreversible motor
disorder, tardive dyskinesia (TD). Although TD is a serious side effect, the
pathophysiology of it remains unclear. This article reviews recent experiments designed
to determine the pathophysiology of TD. The review is divided into three parts ; the
first part describes the existing hypotheses on the pathophysiology of TD, the second
part consists of the animal models of TD. and the third part consists of the other
descriptions of the experimental researches on TD. The challenge for the future is to
integrate these data into a more complete understanding of the pathophysiology of TD.
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KEYWORD
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